CLINICAL-FEATURES OF 201 CASES WITH DUANES-RETRACTION-SYNDROME

Objective To summarize the clinical features of 201 cases with Duane's retraction syndrome (DRS) and discuss its differential diagnosis. Met hods We retrospectively summarized the 201 cases from 1979 to 1996. Th e clinical features including chief complaints, sexual distribution, a ge at first visit, laterality, type of presentation, ocular deviation in the primary position, refractive errors, amblyopia, globe retractio n, change of the palpebral fissure, upshoot and downshoot in adduction , binocular single vision, and its associated ocular and non-ocular an omalies were analysed. Results There were 99 males and 102 females wit h a female-to-male ratio 1:1. The 65.88% of DRS cases had left eye inv olvement with two-to-one predilection for the left eye. The most commo n form of the syndrome was type I (184 patients, 91.54%). Exotropia wa s the most common deviation in the primary gaze (72 patients, 35.8%). Among 118 patients, most had abduction deficits, globe retraction in a dduction, and face-turn as to maintaining single binocular vision. Cro codial tears (26 patients, 11.93%) was the most frequently encounted o cular abnormalities. Conclusions Diagnosis of DRS in a typical case is not difficult, however, children with bilateral abduction deficits wh ich may mimic DRS must be differentiated from the following four motil ity disorders, namely, abducens nerve palsy, Moebius syndrome, congeni tal oculomotor apraxia, and congenital or infantile esotropia.