We studied tracheal intubation conditions produced by the muscle relax
ant, cisatracurium, following induction of anaesthesia with fentanyl (
2 mu g.kg(-1)) and thiopentone (6 mg.kg(-1)). Sixty patients were rand
omly assigned to receive cisatracurium in a single bolus dose of eithe
r 0.15 or 0.20 mg.kg(-1). Tracheal intubation was commenced 120 s afte
r injection of the relaxant. The mean (SD) time taken to achieve intub
ation was significantly shorter in the 0.20 mg.kg(-1) group (137 (16)
a) than the 0.15 mg.kg(-1) group (149 (12) s; p < 0.05). The intubatin
g conditions were better after the larger dose. Our results suggest th
at when anaesthesia is induced using thiopentone, a dose of 0.20 mg.kg
(-1) of cisatracurium is recommended to ensure satisfactory intubating
conditions.