This article suggests that the field of addiction study and treatment
remains in a state of conceptual chaos. The addictions is an emerging
scientific field that lacks conceptual clarity. To develop the precisi
on necessary for scientific advance, we must begin by developing impro
ved definitions of substance use, abuse, dependence, and addiction. Co
mplicating matters, psychoactive substance use is not a necessary and
sufficient cause of addiction. For example, pathological gamblers expe
rience addiction, including tolerance and withdrawal, often in the abs
ence of any drug use. The neurobiology of subjective experience may be
a more important factor in helping to explain addictive behaviors. Co
nsequently, this article concludes that it is improper to consider dru
gs as the necessary precondition for addiction. Better operational def
initions will advance addictions research.