T. Glaus et al., THE ACTIVATED COAGULATION TIME (ACT) - 2 SIMPLE SCREENING-TESTS FOR EVALUATING COAGULATION DISORDERS IN DOGS, Schweizer Archiv fur Tierheilkunde, 138(11), 1996, pp. 532-536
The use of the activated coagulation time (ACT) for testing the intrin
sic coagulation is well established among veterinary practitioners in
the USA. The advantage of the ACT compared to other coagulation tests
is its ease to be performed under practice conditions, The ACT may be
measured manually or instrumentally. The reference range of our instru
mental measurement is between 90 and 120 seconds (median 105 seconds),
of the manual measurement at room temperature between 115 and 145 sec
onds (median 125 seconds). Advantages of the instrumental method are t
he smaller amount of blood (0.4 ml versus 2.0 ml) necessary to perform
the test, and the smaller potential for errors by unexperienced exami
ners. The spread is comparable between the two methods, The most impor
tant cause of false results is poor venipuncture technique: traumatic
venipuncture will trigger the coagulation cascade already during venip
uncture causing an arteficially shortened ACT.