IMPROVED CARDIAC I-123 METAIODOBENZYLGUANIDINE ACCUMULATION AFTER DRUG-THERAPY IN A PATIENT WITH PARKINSONS-DISEASE

A 72-year-old woman with Parkinson's disease and autonomic dysfunction underwent I-123 MIBG cardiac imaging to study sympathetic neuronal in tegrity. This revealed a defect in the infero-posterior wall. Tc-99m s estamibi myocardial perfusion imaging revealed no abnormalities. On fo llow-up I-123 MIBG SPECT, the defect was less prominent and the parkin sonian symptoms were ameliorated by drug therapy. Cardiac I-123 MIBG i maging may be a promising new method for evaluating drug therapy in pa tients with Parkinson's disease.