D. Schwender et al., CENTRAL ANESTHETIC EFFECTS AND SUPPRESSION OF AUDITORY INFORMATION-PROCESSING DURING GENERAL-ANESTHESIA, THEORY IN BIOSCIENCES, 116(3), 1997, pp. 284-289
Several electrophysiological methods have been developed to quantify c
entral anaesthetic effects. Especially, midlatency auditory evoked pot
entials are suppressed in a dose dependent fashion by many general ana
esthetics. This indicates that auditory information processing during
anaesthesia is blocked at the level of the primary auditory cortex dos
e-dependently by general anaesthetics. Furthermore, there is a close c
orrelation between midlatency auditory evoked potentials and complex p
sychological function as wakefulness, awareness, explicit and implicit
memory during anaesthesia. Midlatency auditory evoked potentials seem
to be a promising method to quantify central cortical anaesthetic eff
ects on complex psychological function.