DIETARY CONTROL OF CANCER

Citation
K. Elbayoumy et al., DIETARY CONTROL OF CANCER, Proceedings of the Society for Experimental Biology and Medicine, 216(2), 1997, pp. 211-223
Citations number
134
Categorie Soggetti
Medicine, Research & Experimental
ISSN journal
00379727
Volume
216
Issue
2
Year of publication
1997
Pages
211 - 223
Database
ISI
SICI code
0037-9727(1997)216:2<211:DCOC>2.0.ZU;2-9
Abstract
Many laboratory studies and human epidemiological data suggest that mo st cancer deaths are attributable to lifestyle, including nutritional factors and tobacco and alcohol consumption, Tobacco consumption is ca usally related to cancer of the lung, mouth, larynx, esophagus, bladde r, kidney, and pancreas, Nutrients and nonnutrient dietary components probably account for cancer of the colon, breast, prostate, and stomac h, This report is based on literature and our own data pertaining to t he role of dietary fat, calories, and fiber in the development of colo n and breast cancer, We also discuss the evidence from epidemiological , mechanistic, and preclinical efficacy studies indicating a protectiv e effect of micronutrients, non-nutrients, and certain antioxidants in food against oral and lung cancers, Given the continuing cancer burde n and the relatively slow impact of proven cancer treatment strategies in reducing cancer mortality, it is essential to evaluate promising n utrients and non-nutrients in foods as chemopreventive agents in perso ns at increased risk for cancer, Development of reliable intermediate biomarkers is valuable for clinical chemoprevention intervention trial s, The purpose of this report is to provide the reader with plausible approaches to cancer control.