THE COHEN-SYNDROME - REPORT OF A CASE

We report on a sporadic case satisfied with a proposed diagnostic crit eria for Cohen syndrome. This 10 year-old Japanese boy had truncal obe sity, short stature, mild mental retardation, hypotonia, maxillary hyp oplasia, micrognathia, narrow hands and feet, high-arched palate, prom inent upper central incisors, high nasal bridge, but no pigmentary ret inopathy. Autosomal recessive manner of inheritance was suggested by t he pedigree.