ANTIBIOTIC-INDUCED CONVULSIONS

Convulsive episodes are associated with the use of a number of antimic robial agents. Although seizures may be a feature of the disease being treated, antibiotics should be considered possible causes of seizures , particularly if suggested by temporal relationships between seizure activity and drug administration. The astute clinician should be aware of the clinical settings in which antibiotic-induced seizures occur, be familiar with likely agents and their mechanisms of toxicity, and b e prepared to institute appropriate management directed at this advers e effect of antimicrobial therapy.