S. Kashket et T. Yaskell, EFFECTIVENESS OF CALCIUM LACTATE ADDED TO FOOD IN REDUCING INTRAORAL DEMINERALIZATION OF ENAMEL, Caries research, 31(6), 1997, pp. 429-433
Following the demonstration that rinses with solutions of soluble calc
ium salts reduced sucrose-induced demineralization, a study was undert
aken to determine whether a similar effect could be obtained by the su
pplementation of a solid food with calcium lactate (CL). Subjects wore
palatal appliances containing blocks of bovine enamel that were coate
d with Streptococcus mutans IB 1600 and ate 5-gram portions of cookies
made with defined levels of CL. Determinations were made of changes i
n iodide penetrability (Delta Ip) of the enamel, as well as the pH, ca
lcium and inorganic phosphate of the streptococcal plaque. CL at 3.2%
(w/w) reduced Delta Ip from 12.9+/-1.7 to 6.1+/-0.9 units, i.e. by 52.
7%. Plaque pH was not affected. Demineralization was reduced progressi
vely with increasing concentrations of added CL, and CL was most effec
tive with increasingly sweet cookies. Plaque contained 32.4+/-6.0 and
17.1+/-4.2 mM calcium after 1 and 5 min, respectively. Calculations sh
owed that the plaque was saturated with respect to enamel during the f
irst 5-10 minutes after food ingestion, in spite of the progressive dr
op in plaque pH. In conclusion, the present study demonstrated the red
uction of the cariogenic potential of solid food by relatively low con
centrations of CL. The effect appeared to be related to the ability of
the food to maintain high levels of calcium in the streptococcal plaq
ue during the period of active acidogenesis.