G-PROTEIN BETA-GAMMA SUBUNIT GENES EXPRESSED IN OLFACTORY RECEPTOR NEURONS

Authors
BRUCH RC MEDLER KF TRAN HN HAMLIN JA
Citation
Rc. Bruch et al., G-PROTEIN BETA-GAMMA SUBUNIT GENES EXPRESSED IN OLFACTORY RECEPTOR NEURONS, Chemical senses, 22(5), 1997, pp. 587-592
Citations number
26
Categorie Soggetti
Physiology,Neurosciences,"Behavioral Sciences
Journal title
Chemical senses → ACNP
ISSN journal
0379864X
Volume
22
Issue
5
Year of publication
1997
Pages
587 - 592
Database
ISI
SICI code
0379-864X(1997)22:5<587:GBSGEI>2.0.ZU;2-H
Abstract
The expression of genes encoding G-protein beta gamma subunits was inv estigated in isolated olfactory receptor neurons from channel catfish. DNA sequencing of PCR products showed that the beta 1, beta 2, gamma 2 and gamma 3 genes were expressed in the neurons. Western blotting sh owed that at least three of these subunit proteins were expressed. Thi s first analysis of the expression of beta gamma genes in olfactory re ceptor neurons suggests that these subunits may be involved in a varie ty of transduction events in these cells.