ORAL REHYDRATION WITH A PLANTAIN FLOUR-BASED SOLUTION IN CHILDREN DEHYDRATED BY ACUTE DIARRHEA - A CLINICAL-TRIAL

A clinical trial was conducted in order to prove the efficacy of a sol ution containing 50 g/l of plantain flour and 3.5 g/l of sodium chlori de (NaCl) for the rehydration of children with acute diarrheal disease s. 121 children were given WHO-ORS (Group A) and 117 a plantain flour- based solution (Group B). Rehydration was successful in 85.9% in Group A and 88.0% in Group B (p = 0.634). Rehydration was completed in 5.28 h (SD 1.99) in Group A and in 4.88 h (SD 2.11) in Group B (p = 0.132) . The average solution intake for rehydration was 24.56 ml/kg/h (SD 10 .12) in Group A and 21.17 ml/kg/h (SD 9.35) in Group B (p = 0.00782). The mean stool output during rehydration was 8.45 g/kg/h (SD 9.72) in Group A and 4.69 g/kg/h (SD 4.98) in Group B (p = 0.00053). Decrease i n blood levels of sodium and potassium occurred in some children in gr oup B. The plantain flour-based solution proved effective for the trea tment of dehydration due to acute diarrheal diseases and should be con sidered as an alternative when standard WHO-ORS is not available.