NECROTIZING ENCEPHALITIS IN A YORKSHIRE TERRIER

A 10-year-old spayed female Yorkshire Terrier was admitted because of prolonged onset of neurologic dysfunction that had resulted in multipl e cranial nerve deficits, hydrocephalus, and right-sided brain atrophy and cavitation. Microscopic lesions were characterized by malacia and cavitation within subcortical and periventricular white matter and th e thalamus, accompanied by lymphoplasmacytic perivascular infiltrates in affected areas as well as in adjacent gray matter and the leptomeni nges. Necrotizing encephalitis is morphologically distinct from enceph alitis of Pugs and Malteses and granulomatous meningoencephalitis and should be considered as a cause of localizing lesions of the CNS in Yo rkshire Terriers.