SUCCESSFUL THERAPY OF REFRACTORY ERYTHEMA-NODOSUM ASSOCIATED WITH CROHNS-DISEASE USING POTASSIUM-IODIDE

Erythema nodosum is a common extraintestinal manifestation of Crohn's disease. While mild skin involvement often responds to conservative ma nagement, severe or refractory cases may require systemic corticostero id or immunosuppressive therapy. This report describes successful trea tment of severe, refractory erythema nodosum associated with Crohn's c olitis using oral potassium iodide. While the mechanism of action of t his agent is poorly understood, it appears to be an effective and nont oxic therapy for Crohn's-related erythema nodosum and warrants further evaluation in a placebo controlled trial.