P. Mondola et al., THE CALF SUPEROXIDE-DISMUTASE RECEPTOR OF RAT HEPATOCYTES, Comparative biochemistry and physiology. B. Comparative biochemistry, 108(3), 1994, pp. 309-313
The presence of a specific SOD surface membrane receptor in rat hepato
cyte cells was investigated using ligand blot analysis of the SOD rece
ptor with I-125-SOD, and binding studies with iodinated and fluorescin
ated SOD. A specific SOD receptor with a molecular weight of about 320
kDa was identified. We suggest that the modulatory role of SOD on HMG
-CoA reductase is exerted through this specific receptor.