PREPARATION OF N-BOC N-ALKYL GLYCINES FOR PEPTOID SYNTHESIS

Authors
MOUNA AM NGUYEN C RAGE I XIE J NEE G MAZALEYRAT JP WAKSELMAN M
Citation
Am. Mouna et al., PREPARATION OF N-BOC N-ALKYL GLYCINES FOR PEPTOID SYNTHESIS, Synthetic communications, 24(17), 1994, pp. 2429-2435
Citations number
36
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
24
Issue
17
Year of publication
1994
Pages
2429 - 2435
Database
ISI
SICI code
0039-7911(1994)24:17<2429:PONNGF>2.0.ZU;2-D
Abstract
A series of N-tert-butoxycarbonylated N-allyl, N-propargyl, N-benzyl o r branched N-alkyl glycines, useful building blocks for the synthesis of N-alkyl glycine oligomers, have been prepared by N-alkylation of N- Boc glycine or by a two-step method: reductive alkylation and tert-but oxycarbonylation.