SYNTHESIS OF OCTACARBOXYTETRA(2,3-PYRAZINO)PORPHYRAZINE - NOVEL WATER-SOLUBLE PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY

Authors
KUDREVICH SV GALPERN MG VANLIER JE
Citation
Sv. Kudrevich et al., SYNTHESIS OF OCTACARBOXYTETRA(2,3-PYRAZINO)PORPHYRAZINE - NOVEL WATER-SOLUBLE PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY, Synthesis, (8), 1994, pp. 779-781
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
8
Year of publication
1994
Pages
779 - 781
Database
ISI
SICI code
0039-7881(1994):8<779:SOO-NW>2.0.ZU;2-H
Abstract
The condensation of 2,3-dicyano-5,6-diethoxycarbonylpyrazine with a me tal salt affords ra-2,3-(5,6-diethoxycarbonylpyrazino)porphyrazine, wh ich upon mild hydrolysis yields novel water-soluble metal complexes of tetra-2,3-(5,6-dicarboxypyrazino)porphyrazine. These octaaza analogs of phthalocyanine have potential applications in the field of photodyn amic therapy of cancer.