THE EFFECTS OF CARDIAC-SURGERY ON EARLY AND LATE PULMONARY FUNCTIONS

Background: Impaired pulmonary functions are common in cardiac patient s. Early and late effects of cardiac surgery on pulmonary function tes ts (PFTs) are presented. Methods: Fifty patients undergoing cardiac su rgery (coronary artery bypass grafting [CABG, 74%], valve replacement or valvuloplasty [20%] and combined procedures [6%]) were studied. Ang inal and cardiac failure symptoms severity, and smoking history, were evaluated preoperatively. PFTs were studied and compared pre-, and 3 w eeks and 3.5 months postoperatively. Results: Pre- and postoperative P FTs were inversely related to severity of preoperative symptoms. Force d vital capacity (FVC) dropped from 98% of predicted preoperatively, t o 63% (P<0.00001) and 75% (P<0.00001)3 weeks and 3.5 months post-opera tively, respectively. Expiratory volume in the first 1 s of forced exp iration (FEV1.0) decreased from 95% to 61% (P<0.00001) and 70% (P<0.00 001), respectively. Forced expiratory flow at 50% of vital capacity (F EF50) decreased from 85% to 56% (P<0.00001) and 59% (P<0.00001). Force d expiratory flow at 75% of vital capacity (FEF75) decreased from 77% to 47% and 47% (P<0.00001). Peak expiratory flow rate (PEFR) declined from 101% to 66% (P<0.00001) and 86% (P<0.003). Maximal voluntary vent ilation declined from 103% to 68% (P<0.00001) and 77% (P<0.00001). Onl y FVC (P<0.0003), FEV1.0 (P<0.02) and PEFR (P<0.0001) partially recove red postoperatively. Smoking history did not affect perioperative PFTs . Pre-, but not post-operative FVC, FEV1.0, FEF50 and FEF75 were worse in valve than in CABG patients. Conclusions: Pulmonary functions dete riorate significantly for at least 3.5 months after cardiac surgery. P reoperative cardiac ischaemic and failure symptoms are inversely relat ed to perioperative PFTs. (C) Acta Anaesthesiologica Scandinavica.