Rp. Byington et al., RATIONALE, DESIGN, AND BASE-LINE CHARACTERISTICS OF THE PROSPECTIVE RANDOMIZED EVALUATION OF THE VASCULAR EFFECTS OF NORVASC TRIAL (PREVENT), The American journal of cardiology, 80(8), 1997, pp. 1087
The Prospective Randomized Evaluation of the Vascular Effects of Norva
sc Trial is the first angiographic clinical trial to be designed to te
st whether an agent can slow or even reverse the progression of early
coronary atherosclerosis in patients with documented disease, In addit
ion, a subset of patients are undergoing carotid ultrasound examinatio
ns, providing a unique opportunity to assess and correlate disease pro
gression in 2 arterial beds.