THE EVAPORATIVE LIGHT-SCATTERING DETECTOR - SOME APPLICATIONS IN PHARMACEUTICAL ANALYSIS

Authors
KOHLER M HAERDI W CHRISTEN P VEUTHEY JL
Citation
M. Kohler et al., THE EVAPORATIVE LIGHT-SCATTERING DETECTOR - SOME APPLICATIONS IN PHARMACEUTICAL ANALYSIS, TrAC. Trends in analytical chemistry, 16(8), 1997, pp. 475-484
Citations number
44
Categorie Soggetti
Chemistry Analytical
Journal title
TrAC. Trends in analytical chemistry → ACNP
ISSN journal
01659936
Volume
16
Issue
8
Year of publication
1997
Pages
475 - 484
Database
ISI
SICI code
0165-9936(1997)16:8<475:TELD-S>2.0.ZU;2-4
Abstract
The evaporative light scattering detector allows direct detection of a ll non-volatile compounds regardless of their chemical structure, and therefore it is a valuable tool to determine compounds without chromop hores. This detector can be coupled to liquid chromatography and packe d supercritical fluid chromatography. In this article, the principles are described and some examples of application to pharmaceutical analy sis are given.