Rm. Waruiru et al., EFFICACY OF MORANTEL SUSTAINED-RELEASE TRILAMINATE BOLUS AGAINST GASTROINTESTINAL NEMATODES IN GRAZING DAIRY CALVES IN KENYA, Tropical Animal Health and Production, 29(3), 1997, pp. 129-140
The efficacy of morantel sustained release trilaminate (MSRT) bolus ag
ainst gastrointestinal nematodes was evaluated under field conditions
over a 10-month period. Twenty weaner calves were randomly divided int
o 2 groups of 10 calves each and grazed from March to December on adja
cent, similarly contaminated paddocks. Group 1 calves (T-1) served as
untreated controls while group 2 calves (T-2) were dosed at turnout wi
th MSRT bolus designed to release morantel tartrate continuously for 9
0 days. The efficacy of MSRT was assessed by comparison of parasitolog
ical data (faecal worm egg counts, herbage larval counts, worm counts
from tracer calves and set-stocked trial calves, determination of haem
atological parameters and pepsinogen levels), weight gains and clinica
l status of the animals. Faecal egg counts fr om the treated group (T-
2) were reduced by 100% (P < 0.001) following treatment and remained s
ignificantly (P < 0.05) lower than counts from T-1 calves up to trial
termination. The use of MSRT bolus resulted in a reduction of 92% (P <
0.001) in the number of gastrointestinal nematodes in set-stocked cal
ves at the end of the study and a 55 to 85.7% I reduction in herbage l
arval infectivity as reflected in lowered parasite burdens in tracer c
alves. At the trial termination, the control calves had gained on aver
age (+/-s.d.) 59.4+/-4.8kg (200.0+/-7.4g day(-1)) and the treated ones
on an average 128.6+/-10.5kg (530.0+/-13.1g day(-1)).