SYNCHROTRON-RADIATION APPLICATIONS TO MACROMOLECULAR CRYSTALLOGRAPHY

Progress has been rapid in the development and application of four dif ferent types of macromolecular crystallographic experiment at synchrot ron hard X-ray sources: multiwavelength anomalous diffraction; studies of crystals with very large unit cell dimensions; structure determina tion at atomic or near-atomic resolution; and time-resolved studies. T he results illustrate the interplay between the advanced technical cap abilities available at new beamlines and more challenging scientific i ssues. (C) Current Biology Ltd ISSN 0959-440X