ESTIMATION OF CONDUCTION-VELOCITY DISTRIBUTION BY REGULARIZED-LEAST-SQUARES METHOD

A novel technique for estimating the distribution of the conduction ve locity of peripheral nerve fibers is described in this paper. In order to overcome the sensitivity of present methods to noisy data, a regul arized-least-squares (RLS) method with a smoothing constraint and a se lf-adaption of regularization parameter was adopted. The simulation re sults demonstrated that the improved technique maybe applied in clinic al diagnosis because it yielded reliable and almost undistorted result s even when the simulated data are severely contaminated by noise.