ON THE REACTION OF 2-AMINO-4-THIAZOLINIMINIUM SALTS WITH ACTIVE METHYLENE-COMPOUNDS

Authors
FLAIG R HARTMANN H
Citation
R. Flaig et H. Hartmann, ON THE REACTION OF 2-AMINO-4-THIAZOLINIMINIUM SALTS WITH ACTIVE METHYLENE-COMPOUNDS, Monatshefte fuer Chemie, 128(10), 1997, pp. 1051-1060
Citations number
20
Categorie Soggetti
Chemistry
Journal title
Monatshefte fuer Chemie → ACNP
ISSN journal
00269247
Volume
128
Issue
10
Year of publication
1997
Pages
1051 - 1060
Database
ISI
SICI code
0026-9247(1997)128:10<1051:OTRO2S>2.0.ZU;2-6
Abstract
The easily available 2-amino-4-thiazoliniminium salts 6 react with dif ferent types of active methylene compounds. Whereas 2-amino-4-cyanomet hylene-4,5-dihydrothiazoles 13 and 14 are formed with malononitrile (1 1) or ethyl cyanoacetate (12) in the presence of bases, acetyl acetone (15) and ethyl acetic acetate (16) afford 2-amino-thiazolo[4,5-b]pyri dines 21 and 22, resp. The structures of the new compounds 13, 14, 21 and 22 have been elucidated by means of analytical and spectroscopic m ethods and confirmed by some chemical reactions.