The incidence of epilepsy in 323 patients with cerebral palsy (CP) was
41.8%. Almost half of the patients with spastic tetraplegia and hemip
legia had epilepsy. The incidence was lower in patients with spastic d
iplegia. No sex differences were observed. Partial seizures were by fa
r the most common form of epilepsy in spastic hemiplegia, while genera
lized tonic-clonic episodes predominated in all other forms of CP. A v
ery high incidence of West syndrome was observed in patients with spas
tic tetraplegia. Most of the patients with spastic tetraplegia had the
ir first seizure in the first year of life. In patients with spastic h
emiplegia the onset of epilepsy was often delayed for several years. A
high rate of polytherapy was recorded, but two-thirds of the patients
remained seizure-free for long periods. In just over one-fifth of the
patients successful withdrawal of medication was achieved.