J. Hirschberg et al., MOLECULAR-GENETICS OF THE CAROTENOID BIOSYNTHESIS PATHWAY IN PLANTS AND ALGAE, Pure and applied chemistry, 69(10), 1997, pp. 2151-2158
During recent years genes for more than 20 different carotenogenic enz
ymes have been cloned from various organisms: bacteria, cyanobacteria,
fungi, algae and plants. This accomplishment has provided new molecul
ar tools to study the enzymes and yielded new information on their str
ucture, function and regulation. We describe here the recent progress
in the molecular genetics of the carotenoid biosynthesis pathway in pl
ants. To date, the genes for almost all the enzymes, from the early st
eps of the isoprenoid pathway to the predominant xanthophylls, have be
en cloned. Their characterization had an immense impact on our underst
anding of carotenoid biosynthesis at the molecular level.