Eighteen consecutive cases of fetal tachycardia referred to the depart
ment of Pediatric Cardiology, Uppsala University, were studied retrosp
ectively. All cases were detected at a routine visit at an antenatal c
linic. None of the cases had a structural heart disease. Fetal suprave
ntricular tachycardia was found in 8 cases and atrial flutter in 10 ca
ses. In 7 cases, hydrops and heart failure were diagnosed. Antenatal t
reatment with digoxin, alone or in combination with other antiarrhythm
ic drugs, was needed in 15 cases. In 10 cases an obvious effect of the
therapy was observed. No intrauterine deaths occurred. One infant die
d postnatally. At birth, 4 infants were in need of neonatal intensive
care when delivered. Antiarrhythmic treatment was started in 13 cases
postnatally. Late relapse of tachycardia was reported in 3 children. I
n 1 of these cases the prenatal tachycardia had resolved spontaneously
and the infant was not treated antenatally nor during the neonatal pe
riod. Although fetal tachycardia is a serious condition, antenatal tre
atment in combination with careful monitoring and induction of deliver
y in cases with deteriorating fetal condition result in a satisfactory
outcome for the majority of infants. However, there is a risk of late
recurrence.