MANAGEMENT OF CONGENITAL MICROPHTHALMOS AND ANOPHTHALMOS

Purpose To better-characterize congenital anophthalmos and microphthal mos in order to distinguish which patients need surgical treatment. Ma terials and methods A retrospective study of 42 cases with congenital anophthalmos and microphthalmos over a 16 years period was performed. Seven anophthalmos, 20 microphthalmic globes with Mo associated colobo matous orbital cyst and 15 microphthalmic globes associated with colob omatous orbital cyst were observed. Complete history, pediatricial and ophthalmological examination, electrophysiological feature, oculo-cer ebral imagery and karyotype on each of the patients were reviewed. Res ults Among all patients, lack of development of the lids was observed in 45% of cases. In our group of anophthalmos, 100% had micro-orbit. I n our group of microphthalmic globes with no associated colobomatous o rbital cyst, 30% had micro-orbit and in our group of microphthalmic gl obes associated with colobomatous orbital cyst, 6% had micro-orbit. 75 % of patients had ocular anomalies and 39% had systemic anomalies, mos tly on the face. Aetiology were found in 36% of cases. Visual evoked p otentials and retinal electric feature were useful to better determine visual function. Conclusion Expandable orbital prothesis would appear to be the most effective therapy for certain cases of anophtalmos and microphthalmos with micro-orbit.