Common treatable sleep disorders resulting in excessive daytime sleepi
ness may resemble or contribute to spells of altered responsiveness. T
hese spells may mimic epileptic seizures or other paroxysmal disorders
. Three patients presented with paroxysmal spells of altered responsiv
eness that were attributed initially to epileptic seizures or pseudose
izures. One patient had a history of childhood epilepsy and was referr
ed for the concern of recurrent seizures. In another patient, antiepil
eptic drugs (AEDS) were prescribed for suspected epileptic seizures wi
thout an improvement in spells. After their physicians obtained a hist
ory of excessive daytime sleepiness, snoring, and/or restless leg symp
toms, patients were evaluated with polysomnography, multiple sleep lat
ency tests, electroencephalograms (EEC), and video-EEG monitoring. Sle
ep studies were diagnostic of obstructive sleep apnea, periodic limb m
ovement disorder, and probable narcolepsy. In all patients, spells of
altered responsiveness and excessive daytime sleepiness improved or re
solved with treatment of the sleep disorder or discontinuation of AEDS
. Patients presenting with paroxysmal spells of altered responsiveness
and excessive daytime sleepiness should be evaluated for sleep disord
ers. Identification and treatment of an underlying sleep disorder may
contribute to resolution of their spells. (C) 1997 by Elsevier Science
Inc. All rights reserved.