Ti. Anatol et al., TRIAL OF 3 METHODS OF INTRAOPERATIVE BUPIVACAINE ANALGESIA FOR PAIN AFTER PEDIATRIC GROIN SURGERY, Canadian journal of anaesthesia, 44(10), 1997, pp. 1053-1059
Purpose: To evaluate the relative effectiveness of three techniques of
regional anaesthesia in the provision of postoperative analgesia in c
hildren. Methods: Random assignment was made of 183 children scheduled
for groin surgery to one of three groups. Bupivacaine 0.5% plain (2 m
gkg(-1)) was injected by the surgeon after skin incision. Group A rece
ived wound infiltration. Group B had regional nerve blockade, Group C
had a combination of both methods. Postoperatively, pain was assessed
using the CHEOPS behavioural scale at half hourly intervals until disc
harge home. Satisfactory pain control was arbitrarily defined as a CHE
OPS score of less than or equal to six. Potential differences among th
e groups were sought using graphical representation of mean pain score
s, the frequencies of maximum pain:scores, and the incidence of postop
erative vomiting and oral analgesic consumption. Results: Fifteen pati
ents had to be excluded from analysis. This left 61 patients in Group
A, 55 in Group B, and 52 in Group C. There were no demographic differe
nces among the groups, No differences were demonstrated among the grou
ps either in CHEOPS pain scores at any observation point (P = >0.8), o
r in the incidence of vomiting or need for postoperative analgesia. (P
= 0.52 and P = 0.41 respectively). Overall, 80% of the observations m
ade (1135/1425) met our definition-of satisfactory pain control. A pos
t hoc calculation of the power of the study confirmed sufficient power
to detect a 5% difference among groups. Conclusion: Al three methods
achieved analgesia with 80% of the pain scores meeting our definition
of satisfactory pain control. None of the techniques enjoyed any appar
ent advantage.