CHRONIC GRANULOMATOUS-DISEASE MASQUERADING AS A BLADDER-TUMOR - A POTENTIAL SOURCE OF DIAGNOSTIC ERROR

Chronic granulomatous disease (CGD) is a rare inherited disease of chi ldhood, characterized by recurrent bacterial or fungal infections. The underlying defect is a dysfunction of neutrophil granulocytes interfe ring with their ability to kill phagocytosed microorganisms, Genitouri nary tract involvement has been reported in 38% of these patients. We report a case of CGD in whom the most important findings were urinary bladder tumors at different locations and a subsequent obstruction of the left ureter. A review of the pathogenesis of the disease, potentia l involvement of the urinary tract and treatment is presented.