We report a case of lymphomatoid papulosis which developed in a 29-yea
r-old pregnant woman. She had numerous papules scattered over the inne
r aspect of the left thigh. Histology; of the biopsy specimen demonstr
ated an atypical mononuclear cell infiltration of the dermis. Spontane
ous regression of the lesions occurred after termination of gestation.
A possible effect of hormonal changes and alterations in T lymphocyte
activity during pregnancy on the occurrence of lymphomatoid papulosis
is discussed.