Due to their high synthetic potential in regard to chemo-, regio- and
stereoselectivity, enzymes have started to play an important role in m
odern chemistry. New interesting synthetical pathways were developed,
since it has been shown that lipases are catalytically active even in
anhydrous organic solvents. Although the number of publications dealin
g with enzymatic synthesis in unconventional solvent systems is still
increasing, few works have been published with respect to chemical eng
ineering aspects. In this paper, the optimization of a stereoselective
esterification using lipases in organic solvents is reported.