ACUTE PROMYELOCYTIC LEUKEMIA IN A HIV-SEROPOSITIVE PATIENT

Acute myeloid leukemia (AML) is infrequent in patients with human immu nodeficiency virus (HIV) infection. Among AML, acute promyelocytic leu kemia (APL) has been rarely described in such patients, with only one case bring published. We report a 30 years-old intravenous drug abuser HN-infected male with APL who attained complete clinical, morphologic al, and molecular remission after differentiation therapy with all-tra ns-retinoic acid (ATRA) followed by intensive chemotherapy. The result s of treatment in this patient and in other AML published cases sugges t that therapy for AML should not be modified because of HIV infection if patients have an adequate performance status.