Purpose: Evaluation of a growth model for the biometric parameters of
early pregnancy: Chorionic cavity, yolk sac, amniotic cavity, crown-ru
mp length and biparietal diameter. Method: 618 clinically well-dated s
ingleton pregnancies of the first trimester were measured in a prospec
tive cross-sectional study with high-frequency transvaginal ultrasound
between 28 and 94 days post menstruation. Results: Normal curves (5th
, 50th, 95th percentiles) for all parameters were established using ou
r growth model. The growth curves of chorionic cavity amniotic cavity,
and biparietal diameter showed a linear growth whereas the growth cur
ve of the crown-rump-length represented an exponential curve. Linear g
rowth of the yolk sac was found until 8 weeks of gestation and there w
as no growth alteration after this time. Conclusion: With our growth c
urves of the first trimester it is possible to monitor the embryonic d
evelopment with several parameters.