Extensive and long-standing colitis due to Crohn's disease and ulcerat
ive colitis is associated with an increased incidence of colorectal ca
ncer. Colonoscopy with biopsies for mucosal dysplasia can help stratif
y those patients who are at increased risk. However, the effectiveness
of surveillance programs has been questioned. Newer molecular techniq
ues may eventually lead to the development of more accurate screening
tools, but at this time there is not enough evidence to support their
widespread use.