Ej. Mcguire et Sf. English, PERIURETHRAL COLLAGEN INJECTION FOR MALE AND FEMALE SPHINCTERIC INCONTINENCE - INDICATIONS, TECHNIQUES, AND RESULT, World journal of urology, 15(5), 1997, pp. 306-309
Intrinsic sphincter deficiency is characterized by a poorly functionin
g intrinsic urethral sphincter, which leaks urine at relatively low pr
essures. Patients with this sort of incontinence are candidates for co
llagen implant therapy. Collagen is injected in the region of the blad
der neck with success, depending on the precise placement of the colla
gen. There is generally a need to implant more collagen into men. The
percentage of patients showing improvement in their incontinence after
therapy is 58-100%. Over time the collagen is absorbed and there is a
need to repeat the treatment. Collagen increases the abdominal leak-p
oint pressure without reducing the flow rate or increasing the residua
l volume. Treatment failure does not prevent the performance of other
procedures.