2-CHLORODEOXYADENOSINE (CLADRIBINE) INDUCED ALLERGIC CUTANEOUS REACTIONS WITH EOSINOPHILIA IN A PATIENT WITH B-CELL CHRONIC LYMPHOCYTIC-LEUKEMIA

Authors
ROBAK T SYSAJEDRZEJOWSKA A ROBAK E DABKOWSKI J BLASINSKAMORAWIEC M
Citation
T. Robak et al., 2-CHLORODEOXYADENOSINE (CLADRIBINE) INDUCED ALLERGIC CUTANEOUS REACTIONS WITH EOSINOPHILIA IN A PATIENT WITH B-CELL CHRONIC LYMPHOCYTIC-LEUKEMIA, Journal of medicine, 28(3-4), 1997, pp. 199-209
Citations number
19
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Journal of medicine → ACNP
ISSN journal
00257850
Volume
28
Issue
3-4
Year of publication
1997
Pages
199 - 209
Database
ISI
SICI code
0025-7850(1997)28:3-4<199:2(IACR>2.0.ZU;2-A
Abstract
We present a 68-year old patient with B-cell chronic lymphocytic leuke mia (CLL) treated with 2-chlorodeoxyadenosine (2-CdA). This is the fir st reported patient with B-CLL in whom skin lesions and eosinophilia w ere observed Simultaneously. The most frequent side effect of this dru g is myelosuppression with pancytopenia. So far, there have been few r eports of cases where either skin reactions or eosinophilia, occurring separately, were observed as side effects from 2-CdA treatment.