Uveitis in the pediatric population is not so common, and the etiology
is different from adults. In the present study the charts of the pati
ents with onset of uveitis at 16 years of age or younger were reviewed
in order to analyze the etiology in pediatric patients with uveitis,
and to compare the results with other studies carried out on different
populations. The charts of go cases, followed at the Uvea-Immunology
Clinic of the Cukurova University Medical Faculty Department of Ophtha
lmology, between January 1987 and February 1996 were reviewed retrospe
ctively. There were 47 girls, 43 boys, aged 5-20 (13.64+/-4.24) in the
study group. The average age at onset of uveitis was 12.20+/-4.81, an
d the follow-up period was 9-98 months (21.80+/-11.13). Of the 90 pati
ents 31 (34.4%) had panuveitis, 30 (33.3%) had anterior uveitis, 21 (2
3.3%) had posterior uveitis and 8 (8.9%) had intermediate uveitis. Onl
y 2 (9.5%) of the patients with posterior uveitis were considered idio
pathic after extensive laboratory and clinical work-up, whereas idiopa
thic cases constituted 48.4% of panuveitis, and 46.7% of anterior uvei
tis cases. Of the 90 patients an associated condition could be found i
n only 59 (65.6%) patients. Of these 59 patients 23 had toxoplasmosis
(39%), which constituted the most common associated condition in this
study. The second most common underlying cause was Behcet's disease (1
7%), followed by pars planitis (13.6%), Fuchs' heterochromic iridocycl
itis (8.5%), JRA (5.1%), leukemia (5.1%), and herpetic eye disease (5.
1%) There were single cases with Reiter, toxocariasis, traumatic uveit
is, and sympathetic ophthalmia. Environmental, cultural and genetic fa
ctors may be accountable for the differences in relative frequencies o
f some of the associated conditions between our findings and those of
previously published studies in patients with pediatric uveitis.