O. Bernasconi et al., RECURRENT TOXOPLASMIC RETINOCHOROIDITIS - SIGNIFICANCE OF PERILESIONAL SATELLITE DARK DOTS SEEN BY INDOCYANINE GREEN ANGIOGRAPHY, Ocular immunology and inflammation, 5(3), 1997, pp. 207-211
Purpose: To suggest an explanation for the satellite dark dots seen by
indocyanine green angiography (ICGA) around the main focus of a toxop
lasmic retinochoroiditis. Methods: The authors analysed the evolution
of ICG satellite dark dots in two cases of recurrent toxoplasmic retin
ochoroiditis receiving anti-toxoplasmic treatment not including cortic
osteroids. Results: Both patients had a recurrence on the peripheral a
spect of scars from previous retinochoroiditis and were treated with p
yrimethamine (50 mg/day) and sulfadiazine (4 g/day) for seven weeks. R
esolution of satellite ICG dark dots was observed in both cases on the
follow-up ICG angiogram performed at the end of treatment. Conclusion
: Resolution of ICG satellite dark dots after anti-toxoplasmic treatme
nt not including corticosteroids tends to indicate that there is proba
bly an infectious component in these hypofluorescent dots and that the
y probably do not represent a purely inflammatory perilesional reactio
n.