SALIVARY LEAD AND CADMIUM IN A YOUNG-POPULATION RESIDING IN MEXICO-CITY

Citation
M. Gonzalez et al., SALIVARY LEAD AND CADMIUM IN A YOUNG-POPULATION RESIDING IN MEXICO-CITY, Toxicology letters, 93(1), 1997, pp. 55-64
Citations number
38
Categorie Soggetti
Toxicology
Journal title
ISSN journal
03784274
Volume
93
Issue
1
Year of publication
1997
Pages
55 - 64
Database
ISI
SICI code
0378-4274(1997)93:1<55:SLACIA>2.0.ZU;2-Q
Abstract
Mexico city has a very high pollution index. Based on the view 'that s alivary monitoring can be extended to environmental pollutants', we pe rformed this study in order to determine not only the concentrations o f lead and cadmium in human saliva, but also to establish their possib le association with some socio-demographic factors. One hundred dental students from the National Autonomous University of Mexico living in Mexico city participated in the study. Stimulated human whole saliva s amples were analyzed by atomic absorption spectroscopy. The results sh ow that Pb ((x) over bar=3.10 mu g/dl(-1); maximum (x) over bar=16.8 m u g/dl(-1) and minimum, (x) over bar=0.04 mu g/dl(-1)) and Cd ((x) ove r bar=0.25 mu g/dl(-1); maximum (x) over bar=2.04 mu g/dl(-1) and mini mum (x) over bar=0.004 mu g/dl(-1)) concentrations were higher than th ose reported elsewhere, and that there was no association between seve ral variables studied (age, gender, geographic area and consumption of canned food) and salivary Pb. However, an inverse association was fou nd between Cd and age (chi(2)=5.9012; P less than or equal to 10.05; g amma=-0.5224, P less than or equal to 0.05). From this study it can be concluded that saliva has potential as a technique for monitoring amb ient pollutants recent exposure, since circulating levels of certain p olluting chemicals can be transported into salivary glands and secreti ons. (C) 1997 Elsevier Science Ireland Ltd.