COMPARISON OF ALPHA-TRIFLUOROMETHYLSUBSTITUTED AND BETA-TRIFLUOROMETHYLSUBSTITUTED ACRYLIC ACIDS IN THEIR REACTIONS WITH THIOLS

Authors
VASILEVA TP KOLOMIETS AF MYSOV EI FOKIN AV
Citation
Tp. Vasileva et al., COMPARISON OF ALPHA-TRIFLUOROMETHYLSUBSTITUTED AND BETA-TRIFLUOROMETHYLSUBSTITUTED ACRYLIC ACIDS IN THEIR REACTIONS WITH THIOLS, Russian chemical bulletin, 46(6), 1997, pp. 1181-1183
Citations number
3
Categorie Soggetti
Chemistry
Journal title
Russian chemical bulletin → ACNP
ISSN journal
10665285
Volume
46
Issue
6
Year of publication
1997
Pages
1181 - 1183
Database
ISI
SICI code
1066-5285(1997)46:6<1181:COAAB>2.0.ZU;2-L
Abstract
alpha-(Trifluoromethyl)acrylic acid (1) and gamma,gamma,gamma-trifluor ocrotonic acid (2) add AcSH (exothermally and at 100 degrees C, respec tively) in the absence of a catalyst to form products of beta-thiolati on, which can be easily hydrolyzed to the corresponding beta-mercaptoa lkanoic acids. Thiols also add regiospecifically to acids 1 (in the ab sence of a catalyst) and 2 (only in the presence of trifluoromethanesu lfonic acid as the catalyst) when heated.