STUDIES ON THE SYNTHESIS OF 2 TETRASACCHARIDES AND THE REACTIVITY DIFFERENCE BETWEEN THEM

Authors
ZHU XX CAI MS ZHOU RL
Citation
Xx. Zhu et al., STUDIES ON THE SYNTHESIS OF 2 TETRASACCHARIDES AND THE REACTIVITY DIFFERENCE BETWEEN THEM, Carbohydrate research, 303(3), 1997, pp. 261-266
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Carbohydrate research → ACNP
ISSN journal
00086215
Volume
303
Issue
3
Year of publication
1997
Pages
261 - 266
Database
ISI
SICI code
0008-6215(1997)303:3<261:SOTSO2>2.0.ZU;2-8
Abstract
Studies on the reactivity of two synthetic tetrasaccharides as glycosy l accepters showed that condensation of the methyl alpha-glycoside wit h a disaccharide donor afforded a hexasaccharide, but condensation of the methyl beta-glycoside with the disaccharide did not yield the corr esponding hexasaccharide under the same conditions. A combination of t heoretical results and 2D NMR indicated that the reactivity difference between the methyl alpha-glycoside and the methyl beta-glycoside was determined mainly by steric effects. (C) 1997 Elsevier Science Ltd.