ANTIINFECTIVE ACTIVITY OF A PLANT PREPARATION FROM GERANIUM-SANGUINEUM L

Authors
Citation
J. Serkedjieva, ANTIINFECTIVE ACTIVITY OF A PLANT PREPARATION FROM GERANIUM-SANGUINEUM L, Die Pharmazie, 52(10), 1997, pp. 799-802
Citations number
23
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
ISSN journal
00317144
Volume
52
Issue
10
Year of publication
1997
Pages
799 - 802
Database
ISI
SICI code
0031-7144(1997)52:10<799:AAOAPP>2.0.ZU;2-S
Abstract
A methanol extract (PC) has been obtained from the Bulgarian medicinal plant Geranium sanguineum L. The antiinfective activity of the plant preparation was studied. The extract inhibited the reproduction of a r ange of viruses (influenza, herpes simplex, vaccinia, HIV-I) in cell c ultures. Its antiinfluenza effect was most pronounced; PC reduced the infectivity of various influenza virus strains in vitro and protected mice in experimental influenza infection. The polyphenol extract inhib ited the in vitro growth of Staphylococcus aureus and Candida albicans .