K. Bourantas et al., APLASTIC-ANEMIA - REPORT OF A CASE WITH RECURRENT EPISODES IN CONSECUTIVE PREGNANCIES, Journal of reproductive medicine, 42(10), 1997, pp. 672-674
BACKGROUND: Aplastic anemia complicating normal pregnancy is a rare ev
ent, associated with increased risks for both mother and fetus. CASE:
A 30-year-old woman in her fifth pregnancy experienced the complicatio
ns of aplastic anemia and preeclampsia. The patient had a history of f
our unsuccessful previous pregnancies also complicated by aplastic ane
mia, but she was free of the disease in the intervals between the preg
nancies. During this last pregnancy she presented at 31 weeks' gestati
on with symptoms and signs of severe aplastic anemia and preeclampsia.
A cesarean section was performed, and a normal infant was born. Suppo
rtive therapy, growth factors, prednisolone and intravenous immunoglob
ulin were administered, and the patient's general condition improved t
wo weeks after delivery. CONCLUSION: Aplastic anemia may occur during
consecutive pregnancies. The gestational age at the onset of the disea
se and the severity of the symptoms determine the outcome of the pregn
ancy.