For a general use of the frequency-magnitude (FM) relation in seismic
risk assessment, we formulate a multi-scale approach that relies on th
e hypothesis that only the ensemble of events that are geometrically s
mall, compared with the elements of the seismotectonic regionalization
, can be described by a log-linear FM relation. It follows that the se
ismic zonation must be performed at several scales, depending upon the
self-similarity conditions of the seismic events and the linearity of
the log FM relation, in the magnitude range of interest. The analysis
of worldwide seismicity, using the Harvard catalog, where the seismic
moment is recorded as the earthquake size, corroborates the idea that
a single FM relation is not universally applicable. The multi-scale m
odel of the FM relation is tested in the Italian region.