FINE-NEEDLE ASPIRATION CYTOLOGY OF MAMMARY FIBROMATOSIS - REPORT OF 2CASES

The purpose of this study is to evaluate cytologically two cases of ma mmary fibromatosis (MF). Prior to FNAC, clinical and mammographic susp icion of carcinoma and fibroadenoma were present. In both cases cytolo gy disclosed the presence of numerous spindle cells admixed with epith elial cells. In the first case, carcinoma was excluded and the diagnos is of ''spindle-cell proliferative lesion'' was established. The secon d case was erroneously diagnosed as ''cellular fibroadenoma'' due to t he presence of monolayered ductal epithelial groups and stromal tissue . In both cases local excision of the lesion was recommended. Although in a strict sense fibromatosis is a pure stromal lesion, the frequent presence of epithelial groups in the smears should raise a differenti al diagnosis with other more frequent mixed (epithelial and stromal) l esions such as fibroadenoma, cystosarcoma phyllodes, and metaplastic c arcinoma. Due to the fact that clinically and mamographically MF is fr equently confused with malignancy, preoperative recognition is essenti al since in many cases it would avoid unnecessary radical surgery. In this sense cytology offers very important preoperative information. (C ) 1997 Wiley-Liss, Inc.