A 47-yr-old man with history of metastatic low-grade rectal leiomyosar
coma presented with progressive protrusion of his left eye due to an e
nlarging orbital mass. The differential diagnosis included tumor metas
tasis or orbital infection due to an unknown infectious agent. Diagnos
tic fine-needle aspiration (FNA) of the orbit was performed on an urge
nt basis to institute proper therapy and to save the patient's eyesigh
t. Cytomorphologic examination of the material demonstrated a spindle-
cell neoplasm consistent with metastatic leiomyosarcoma.It is a rare e
vent for leiomyosarcoma to occur in the orbit. On our review of the li
terature, the cytology of primary orbital leiomyosarcoma on FNA has on
ly been reported once. To our knowledge, this is the first report of t
he FNA cytomorphology of netastatic leiomyosarcoma to the orbit. (C) 1
997 Wiley-Liss, Inc.