EARLY HIGH-DOSE INTRAVENOUS METHYLPREDNISOLONE IN ACUTE DISSEMINATED ENCEPHALOMYELITIS - A SUCCESSFUL RECOVERY

We describe a patient with acute disseminated encephalomyelitis (ADEM) who was treated with high-dose intravenous methylprednisolone 2 days after onset of neurologic symptoms. Despite poor prognostic factors an d extensive white matter lesions, the patient recovered dramatically w ith no need for maintenance steroid therapy. This case report of fulmi nant ADEM treated successfully with early high-dose intravenous methyl prednisolone, although uncontrolled, suggests that this agent should b e studied in other cases.