RHODIUM-CATALYZED REACTION OF N-ACYLPIPERAZINES WITH CO AND ETHYLENE - CARBONYLATION AT A C-H BOND DIRECTED BY AN AMIDO GROUP

Authors
ISHII Y CHATANI N KAKIUCHI F MURAI S
Citation
Y. Ishii et al., RHODIUM-CATALYZED REACTION OF N-ACYLPIPERAZINES WITH CO AND ETHYLENE - CARBONYLATION AT A C-H BOND DIRECTED BY AN AMIDO GROUP, Tetrahedron letters, 38(43), 1997, pp. 7565-7568
Citations number
32
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
43
Year of publication
1997
Pages
7565 - 7568
Database
ISI
SICI code
0040-4039(1997)38:43<7565:RRONWC>2.0.ZU;2-U
Abstract
The reaction of N-acylpiperazines with CO (15 atm) and ethylene at 160 degrees C in the presence of Rh-4(CO)(12) results in dehydrogenation and carbonylation at a C-H bond. This reaction represents the first ex ample of carbonylation at a C-H bond promoted by an oxygen functional group. (C) 1997 Elsevier Science Ltd.